Rabbit Secondary Antibodies
Cayman Chemical 5-fluoro AB-7-PAICA 5mg
An analytical reference standard that is categorized as a synthetic cannabinoid; intended for research and forensic applications
Apexbio Technology LLC Cy5 Rabbit Anti-Goat IgG (H+L) Antibody 2X1ml
Cy5 Rabbit Anti-Goat IgG HplusL Antibody is a fluorescence-labeled secondary antibody targeting goat immunoglobulin G (IgG) specifically binding both heavy and light chains It is designed for signal amplification in immunological assays by binding to primary goat IgG antibodies enabling sensitive detection of target antigens Cy5 Rabbit Anti-Goat IgG HplusL Antibody exerts its biological activity by binding to goat IgG primary antibodies enabling visualization through the Cy5 fluorophore (excitation/emission 650/670 nm) Based on these properties Cy5 Rabbit Anti-Goat IgG HplusL Antibody holds research potential in immunofluorescence staining flow cytometry western blotting and ELISA applications
ABclonal Technology 594 Rabbit anti- CD130/gp130
Contributes to interleukin-11 binding activity and interleukin-11 receptor activity Involved in interleukin-6-mediated signaling pathway intestinal epithelial cell development and positive regulation of Notch signaling pathway Acts upstream of or within several processes including glycogen metabolic process positive regulation of astrocyte differentiation and regulation of Notch signaling pathway Located in dendrite external side of plasma membrane and neuronal cell body Is expressed in several structures including alimentary system brain early conceptus immune system and reproductive system Used to study rheumatoid arthritis and stomach cancer Human ortholog(s) of this gene implicated in arteriosclerosis hyper IgE recurrent infection syndrome 4 and hyperandrogenism Orthologous to human IL6ST (interleukin 6 cytokine family signal transducer)
Sigma Aldrich Fine Chemicals Biosciences SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES
NC3972427 ANTI-IL6R AB IN RBT 100UG
Cayman Chemical Pax5CTerm RabbIt Monclon 100uL
A RIPK2 inhibitor inhibits RIPK2 by 65 in a kinase assay at 10 UM inhibits VEGFR3 by greater than 90 as well as 14 additional kinases by 60-89 in a panel of 344 kinases at 10 UM reduces colonic damage in a mouse model of TNBS-induced colitis at 7.5 and 145 mg/kg twice per day a prodrug
ABclonal Technology CD45RB Rabbit mAb
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth differentiation mitosis and oncogenic transformation This PTP contains an extracellular domain a single transmembrane segment and two tandem intracytoplasmic catalytic domains and thus is classified as a receptor type PTP This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling It functions through either direct interaction with components of the antigen receptor complexes or by activating various Src family kinases required for the antigen receptor signaling This PTP also suppresses JAK kinases and thus functions as a regulator of cytokine receptor signaling Alternatively spliced transcripts variants of this gene which encode distinct isoforms have been reported
Cayman Chemical ITGAMCD11bCTerm RabbIt M 100uL
The nucleoside form of hypoxanthine a product of DNA damage that is formed from 2-deoxyadenosine by adenosine deaminase or RNS enhances 5-FU-induced apoptosis in HT-29 and SW620 cancer cells enhances 5-FU-induced tumor growth suppression in an SW620 mouse xenograft model at 1.6 g/kg
Cayman Chemical EGFRCTerm RabbIt Monclon 100uL
A PKC inhibitor (IC50s 1.9 and 0.4 nM for PKCa and PKCθ respectively) selective for PKCa and PKCθ over GSK3B (IC50 3100 nM) inhibits proliferation of TMD8 B cell lymphoma and 92.1 uveal melanoma cells (IC50s 900 and 184 nM respectively) but not SK-MEL-28 skin melanoma cells (IC50 10000 nM)
Cayman Chemical CD20CTerm RabbIt Monclon 100uL
A selective estrogen receptor covalent antagonist covalently modifies cysteine 530 in the ligand binding domain of wild-type ERa and ERaY537S inhibits expression of the ERa target genes GREB1 and TFF1 in MCF-7 cells overexpressing wild-type ERa (IC50s 2.74 and 1.3 nM respectively) ERaY537S (IC50s 29.38 and 19.4 nM respectively) ERaY537N (IC50s 8.14 and 6.1 nM respectively) ERaY537C (IC50s 12.19 and 9.5 nM respectively) or ERaD538G (IC50s 24.87 and 4 nM respectively) inhibits the growth of MCF-7 cells overexpressing wild-type ERa or ERaY537S (GI50s 1.3 and 8.3 nM respectively) reduces tumor growth in an MCF-7 mouse xenograft model and an ERaY537S/WT ST941 PDX mouse model in a dose-dependent manner